Skip to Content
Medical Term:


Pronunciation: sol-vol'i-sis


  1. The reaction of a dissolved salt with the solvent to form an acid and a base; the (partial) reverse of neutralization. If the solvent is water, an amphiprotic solvent, solvolysis is called hydrolysis.
  2. The reaction of the solvent with a solute, resulting in the scission of a bond and incorporation of the atoms of the solvent into the product.
© Copyright 2016 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.