Definition: grossly, a collection of striated voluntary muscle fibers connected at either or both extremities with the bony framework of the body; may be appendicular or axial; histologically, a muscle consisting of elongated, multinucleated, transversely striated skeletal muscle fibers together with connective tissues, blood vessels, and nerves; individual muscle fibers are surrounded by fine reticular and collagen fibers (endomysium); bundles (fascicles) of muscle fibers are surrounded by irregular connective tissue (perimysium); the entire muscle is surrounded, except at the muscle tendon junction, by a dense connective tissue (epimysium).
Synonym(s): musculus skeleti
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