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simian crease


Definition: a single transverse palmar crease formed by fusion of the proximal and distal palmar creases, so called because of its similarity to the transverse flexion crease seen in some monkeys; a common but not pathognomonic feature of Down syndrome; also found in 1% of the normal population.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.