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sickle cell-thalassemia disease


Definition: anemia clinically resembling sickle cell anemia, in which those affected are compound heterozygous for the sickle cell gene and a thalassemia gene; about 60–80% of hemoglobin is Hb S, up to 20% Hb F, and the remainder Hb A.

Synonym(s): microdrepanocytic anemia

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.