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serum sickness

 

Definition: an immune complex disease appearing some days (usually 1–2 weeks) after injection of a foreign serum or serum protein, with local and systemic reactions such as urticaria, fever, general lymphadenopathy, edema, arthritis, and occasionally albuminuria or severe nephritis; originally described in patients receiving serotherapy. The term is sometimes used for clinically similar allergic reactions to drugs.

Synonym(s): serum disease, serum reaction

See Also: immune complex disease

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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