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Sertoli-cell-only syndrome

Pronunciation: ser-to'le

Definition: the absence from the seminiferous tubules of the testes of germinal epithelium, only Sertoli cells are present; there is sterility due to azoospermia but no other sexual abnormality, Leydig cells are normal, but the level of gonadotrophins in the plasma and urine is increased; probably represents one form of seminiferous tubule dysgenesis.

Synonym(s): del Castillo syndrome

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.