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Pronunciation: se'ro-neg'a-tiv

Definition: Lacking an antibody of a specific type in serum; used to mean absence of previous infection with a specific agent (rubella virus), disappearance of antibodies after treatment of a disease (syphilis), or absence of antibody usually found in a given syndrome (rheumatoid arthritis without rheumatoid factor).

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.