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Pronunciation: se'kwes-tra'shun


  1. Formation of a sequestrum.
  2. Loss of blood or of its fluid content into spaces within the body so that it is withdrawn from the circulating volume, resulting in hemodynamic impairment, hypovolemia, hypotension, and reduced venous return to the heart.

[L. sequestratio, fr. sequestro, pp. -atus, to lay aside]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.