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Semple vaccine

Pronunciation: sem'pel

Definition: a modification of the original (Pasteur) rabies vaccine, formerly widely used in the U.S., prepared from rabbit nerve tissue, inactivated with phenol and administered in 14–21 daily injections; has variable potency and is associated with a high incidence of postvaccinal demyelination.

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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