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secretase

Pronunciation: se-kre'tas

Definition: A proteinase that acts on amyloid precursor protein to produce peptides that do not contain the entire amyloid ß protein (a major constituent of the plaques found in Alzheimer disease), are soluble, and do not precipitate to produce amyloid.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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