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Pronunciation: skle'ro-ti-lo'sis

Definition: Atrophic fibrosis of the skin, hypoplasia of the nails, and palmoplantar keratoderma; associated with skin and gastrointestinal cancers; autosomal dominant inheritance.

Synonym(s): scleroatrophy

[sclero- + G. tylosis, the process of becoming callous]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.