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sclerosing adenosis


Definition: a nodular, benign breast lesion occurring most frequently in relatively young women and consisting of hyperplastic distorted lobules of acinar tissue with increased collagenous stroma; the changes may be difficult to distinguish microscopically from carcinoma. Additionally, a benign nodular microscopic lesion of the prostate consisting of acinar tissue with increased stroma; the basal cell layer shows characteristic smooth muscle metaplasia.

Synonym(s): adenofibrosis, fibrosing adenomatosis, fibrosing adenosis

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.