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Pronunciation: skle'ro-der'ma

Definition: Thickening and induration of the skin caused by new collagen formation, with atrophy of pilosebaceous follicles; either a manifestation of progressive systemic sclerosis or localized (morphea).

See: systemic sclerosis, morphea

Synonym(s): systemic scleroderma, systemic sclerosis2

[sclero- + G. derma, skin]

Further information

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.