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Medical Term:


Pronunciation: sklē′rō-der′mă

Definition: Thickening and induration of the skin caused by new collagen formation, with atrophy of pilosebaceous follicles; either a manifestation of progressive systemic sclerosis or localized (morphea).

See: systemic sclerosis, morphea

Synonym(s): systemic scleroderma, systemic sclerosis2

[sclero- + G. derma, skin]