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Schmidt-Thannhauser method

Pronunciation: shmit tahn'how-zer

Definition: a method for fractionation of nucleic acid, based upon the fact that RNA (but not DNA) is hydrolyzed to nucleotides by alkali; RNA can be hydrolyzed in about 2 hours in 0.75 n NaOH, but 18 hours and 0.3 n NaOH usually are used.

[Gerhard Schmidt, S. J. Thannhauser]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.