Pronunciation: shif sher'ing-ton
Definition: when the spinal cord is transected in the midthoracic region or a little lower, the stretch and other postural reflexes of the upper extremity become exaggerated; if the transection is made in the sacral cord, a similar effect is observed in the lower limbs. The effect is regarded as a release phenomenon, release from an inhibitory influence normally exerted by the spinal segments below the transection.
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Examples: glitazone, GI cocktail, etc.