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sarcosine

Pronunciation: sar'ko-sen

Definition: an intermediate in the metabolism of choline; it can donate a methyl group to tetrahydrofolate, yielding N5,N10-methylenetetrahydrofolate; demethylation by sarcosine dehydrogenase yields formaldehyde, glycine, and a reduced acceptor; elevated in certain inherited disorders.

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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