Definition: Conversion into soap, denoting the hydrolytic action of an alkali on fat, especially on triacylglycerols; in histochemistry, saponification is used to demethylate or reverse blockage of carboxylic acid groups, thus permitting basophilia to occur.
[sapo- (sapon-) + L. facio, to make]
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Examples: glitazone, GI cocktail, etc.