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Medical Term:

RNase T1


a nuclease that endonucleolytically cleaves ribonucleic acids at the 3'-5' link of a guanosine 3'-phosphate residue, producing oligonucleotides terminating in this nucleotide; a transferase (endonuclease) in the first (cyclizing) step, a phosphodiesterase on the second (hydrolyzing) step.

Synonym(s): guanyloribonuclease, RNase N1

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