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RNA tectonics

 

Definition: Laboratory-based construction of RNA nanoscopic supramolecules of predictable shape based on ordering of hairpin loops and the arrangement of the reactive molecular terminals. Individual RNA molecules are termed tectoRNAs, and assembly is guided by such entities as noncovalent loop-loop intermediaries termed kissing-loop complexes. Assembled constructs are named with the prefix tecto-, such as tectosquare.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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