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ribonucleotide reductase


Definition: a protein complex that converts ribonucleotide diphosphates (NDPs) such as ADP and CDP to 2'-deoxyribonucleotide diphosphates (dNDPs) such as dADP and dCDP. This complex requires thioredoxin, thioredoxin reductase, and NADPH. It is crucial for DNA synthesis.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.