- The manifestation in an individual of certain characteristics, peculiar to a remote ancestor, which have been suppressed during one or more of the intermediate generations.
- The return to the original phenotype, either by reinstatement of the original genotype (true reversion) or by a mutation at a site different from that of the first mutation, which cancels the effect of the first mutation (suppressor mutation).
[L. reversio (see reversal)]
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Examples: glitazone, GI cocktail, etc.