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Pronunciation: ret'ro-grad


  1. Moving backward.
  2. Degenerating; reversing the normal order of growth and development.
  3. Used in neuroscience to describe distal-proximal flow, movement, or transport in an axon toward its cell body, or degeneration of an axon proximal to a point of injury, such degenerative changes may extend to, and include, the cell body.

[L. retrogradus, fr. retro- + gradior, to go]

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.