retinoic acid embryopathy
Definition: characteristic pattern of mental and physical birth defects that results from maternal use of retinoids, the synthetic derivatives of vitamin A, during pregnancy. The most well known retinoid is isotretinoin, a drug used to treat severe cystic acne. Features may include growth delays, malformations of the skull and facial region, and central nervous system and cardiac abnormalities.
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Examples: glitazone, GI cocktail, etc.
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