restless legs syndrome
a sense of indescribable uneasiness, twitching, or restlessness that occurs in the legs after going to bed, frequently leading to insomnia, which may be relieved temporarily by walking about; thought to be caused by inadequate circulation or as a side effect of some SSRIs and other psychotropic medications.
See Also: akathisia
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Examples: glitazone, GI cocktail, etc.