Definition: A genus of viruses now currently called Orthoreovirus (family Reoviridae) that are 80 nm in diameter, with distinct double layers of capsomeres, and have vertebrates as hosts; they have been recovered from children with upper respiratory tract infections, mild fever, and sometimes diarrhea, and from children with no apparent infection; from chimpanzees with coryza; monkeys, mice; and cattle feces. There are three antigenically distinct human types related by a common complement-fixing antigen and at least 12 avian orthoreoviruses.
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