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renin-angiotensin-aldosterone system


Definition: three hormones, renin, angiotensin, and aldosterone working together to regulate blood pressure. A sustained fall in blood pressure causes the kidney to release renin, which is converted to angiotensin in the circulation; angiotensin then raises blood pressure directly by arteriolar constriction and stimulates the adrenal gland to produce aldosterone, which promotes sodium and water retention by the kidney, such that blood volume and blood pressure increase.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.