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ras oncogene


Definition: point mutations first described in rat sarcoma cells that can be shown to have transforming activity in culture as well as in tumorigenesis models in mice; the ras gene family is composed of three closely related genes on three different chromosomes; abnormalities have been identified in a variety of human tumors.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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