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raphe nuclei


Definition: collective term denoting a variety of nerve cell groups in and along the median plane of the medulla oblongata [nucleus raphes obscurus [TA] (obscure raphe nucleus [TA]), nucleus raphes pallidus [TA] (pallidal raphe nucleus [TA]), and caudal portions of the nucleus raphes magnus [TA] (magnus raphe nucleus [TA])]; of the pons [rostral portions of the nucleus raphes magnus [TA] (magnus raphe nucleus [TA]), nucleus raphes pontis [TA] (pontine raphe nucleus [TA]), nucleus raphes medianus [TA] (median raphe nucleus [TA] or superior central nucleus [TAalt]), and caudal portions of the nucleus raphes posterior [TA] (posterior raphe nucleus [TA]) or dorsal raphe nucleus [TAalt])]; and of the mesencephalon [rostral portions of the nucleus raphe posterior [TA] (posterior raphe nucleus [TA]), nucleus linearis inferioris [TA] (inferior linear nucleus [TA]), nucleus linearis intermedius [TA] (intermediate linear nucleus [TA]), and nucleus linearis superior [TA] (superior linear nucleus [TA])]. These nuclei include neurons characterized by their containing the indolamine transmitter agent serotonin; their serotonin-carrying axons extend rostrally to the hypothalamus, septum, hippocampus, and cingulate gyrus and include projections to brainstem, cerebellum, and spinal cord.

Synonym(s): nuclei raphesTA

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.