a systemic condition caused by substantial whole-body irradiation, seen after nuclear explosions or accidents, rarely after radiotherapy. Manifestations depend on dosage, ranging from anorexia, nausea, vomiting, and mild leukopenia, to thrombocytopenia with hemorrhage, severe leukopenia with infection, anemia, central nervous system damage, and death.
Synonym(s): radiation poisoning
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Examples: glitazone, GI cocktail, etc.