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quinuclidinyl benzilate

Pronunciation: kwi-nuk'li-din'il ben'zi-lat

Definition: A highly potent anticholinergic agent exhibiting 50- to 100-fold greater potency over atropine in binding with and blocking muscarinic cholinergic receptors. Originally developed as a potential military incapacitating agent, it is currently extensively used as a radioactive agent (usually tritiated —H3 —QNB) to identify and label muscarinic receptors in pharmacologic studies.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.