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Q-banding stain


Definition: a fluorescent stain for chromosomes that produces specific banding patterns for each pair of homologous chromosomes; centromeric regions of human chromosomes 3, 4, and 13 are specifically stained, as are satellites of some acrocentric chromosomes and the end of the long axon of the Y chromosome; banding patterns are similar to those obtained with G-banding stain; similar fluorescent stain results are seen with the antibiotics adriamycin and daunomycin, as well as tertiary dyes (butyl proflavine and DAPI), and the bisbenzimidazole dye Hoechst 33258.

Synonym(s): quinacrine chromosome banding stain

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.