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pyruvate kinase


Definition: a phosphotransferase catalyzing transfer of phosphate from phosphoenolpyruvate to ADP, forming ATP and pyruvate; other nucleoside phosphates can participate in the reaction; a key step in glycolysis; a deficiency in pyruvate kinase will lead to hemolytic anemia.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.