Skip to Content
Medical Term:

PRPP synthetase

Pronunciation: sin'the-tas

Definition: An enzyme that catalyzes the reaction of a-d-ribose 5-phosphate and ATP to produce PRPP and AMP; a regulatory enzyme in purine and pyrimidine biosynthesis; enhanced activity of this enzyme results in an increase in purine biosynthesis leading to gout.

© Copyright 2016 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.