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properdin

Pronunciation: pro'per-din

Definition: A control protein for the alternate complement cascade, properdin stabilizes the C3 convertase enzyme, a deficiency of which increases susceptibility to systemic meningococcal infections and can be inherited in an x-linked pattern.

[pro- + L. perdo, to destroy]

See Also: properdin system, component of complement, factor P

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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