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proliferating cell nuclear antigen


Definition: a nuclear nonhistone protein with a molecular weight of 36-kD that plays a role in the initiation of cell proliferation by augmenting DNA polymerase; stains for proliferating cell nuclear antigen in tumors correlated with grade and mitotic activity.

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.