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programmed cell-death 1


Definition: A transmembrane protein found on various mammalian cells that plays a key role in immune suppression when it binds to its receptor, programmed death-1, present on some immune cells. Expression of PD-L1 on malignant cells may be a means of avoiding recognition of immunity.

Synonym(s): CD274, B7 homologue 1, PD-L1

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.