Skip to Content

programmed cell-death 1


Definition: A transmembrane protein found on various mammalian cells that plays a key role in immune suppression when it binds to its receptor, programmed death-1, present on some immune cells. Expression of PD-L1 on malignant cells may be a means of avoiding recognition of immunity.

Synonym(s): CD274, B7 homologue 1, PD-L1

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.