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Pronunciation: pro-je're-a

Definition: A condition of precocious aging with onset at birth or early childhood; characterized by growth retardation, a senile appearance with dry wrinkled skin, total alopecia, and birdlike facies; early occurrence of atherosclerosis in blood vessels and premature death due to coronary artery disease; genetics unclear.

Synonym(s): Hutchinson-Gilford disease, Hutchinson-Gilford syndrome, premature senility syndrome

[pro- + G. geras, old age]

Further information

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.

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