primary ovarian follicle
Definition: an ovarian follicle before the appearance of an antrum; marked by developmental changes in the primary oocyte and follicular cells so that the latter form one or more layers of cuboidal or columnar cells; the follicle becomes surrounded by a sheath of stroma, the theca.
Synonym(s): folliculus ovaricus primarius
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Examples: glitazone, GI cocktail, etc.