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Prausnitz-Küstner reaction

Pronunciation: prows'nits kist'ner

Definition: a test for the presence of immediate hypersensitivity in humans; test serum from an atopic individual is injected intradermally into a normal subject; the normal subject is challenged 24–48 hours later with the antigen suspected of causing the immediate hypersensitivity reaction in the atopic subject, usually in the form of a wheal flare. (Note: P-K tests are no longer performed because of risk of transmitting disease.)

Synonym(s): P-K test

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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