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Medical Term:

positive/negative chronotrope

Pronunciation: poz'i-tiv-neg'a-tiv kroo'no-trop


an agent or medication, or its side effects, which may effectuate to either slow (negative) or accelerate (positive) the rate of a functional system (usually the heart).

See Also: chronotropism

© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.