porphyria cutanea tarda
Definition: familial or sporadic porphyria characterized by liver dysfunction and photosensitive cutaneous lesions, with bullae, hyperpigmentation, and sclerodermalike changes in the skin and increased excretion of uroporphyrin; caused by a deficiency of uroporphyrinogen decarboxylase induced in sporadic cases by chronic alcoholism; autosomal dominant inheritance in familial cases.
Synonym(s): symptomatic porphyria
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