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porphobilinogen synthase

 

Definition: a liver enzyme catalyzing the formation of porphobilinogen and water from two molecules of ?-aminolevulinate, an important reaction in porphyrin biosynthesis; inhibited by lead in cases of lead poisoning; a deficiency of this enzyme results in elevated levels of ?-aminolevulinate and results in neurologic disturbances.

Synonym(s): ?-aminolevulinate dehydratase

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© Copyright 2017 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.
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