Definition: the diamond-shaped space posterior to the knee joint bounded superficially by the diverging biceps femoris and semimembranosus muscles above and inferiorly by the two heads of the gastrocnemius muscle; deeply, the fossa is bound superiorly by the diverging supracondylar lines of the femur and the soleal line of the tibia inferiorly. Contents: tibial nerve, popliteal artery, vein, fat.
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Examples: glitazone, GI cocktail, etc.