Definition: A condition in which splenic tissue is divided into nearly equal masses or totally absent; congenital heart disease and malposition and maldevelopment of abdominal organs are common; may be related to situs inversus. Most cases are sporadic, although some suggest autosomal recessive inheritance.
[poly- + G. splen, spleen]
See Also: bilateral left-sidedness
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Examples: glitazone, GI cocktail, etc.