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Medical Term:


Pronunciation: pol′ē-ra-dik′yū-lō-nū-rop′ă-thē


  1. Literally, a disease process that affects roots and peripheral nerves.
  2. A nontraumatic, usually sporadic, generalized disorder of nerve roots and peripheral nerves, which may affect motor fibers or sensory fibers, but usually both, although often not to the same degree; classified as axon degenerating (axonal) or demyelinating. This disorder has many causes, primarily immune mediated, and includes Guillain-Barré syndrome and chronic inflammatory polyneuropathy.