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Pronunciation: pol'e-nu'kle-o'ti-das'ez


  1. Enzymes catalyzing the hydrolysis of polynucleotides to oligonucleotides or to mononucleotides; phosphodiesterases, nucleases.
  2. Term once applied to the two polynucleotide phosphatases, 2'(3')- and 5'-, which do not cleave internucleotide links.
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