Skip to Content

poliodystrophia cerebri progressiva infantilis


Definition: autosomal recessively inherited progressive spastic paresis of extremities with progressive mental deterioration, with development of seizures, blindness, and deafness, beginning during the first year of life, and with destruction and disorganization of nerve cells of the cerebral cortex.

Synonym(s): Alpers disease, Christensen-Krabbe disease, progressive cerebral poliodystrophy

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review date: Sep 19, 2016.