Definition: Abnormal presence of air in mediastinal tissues; multiple causes include pulmonary interstitial emphysema, ruptured bleb, perforation of the cervical or thoracic esophagus or airways, cervicomediastinal infection, and perforated abdominal viscus.
Synonym(s): mediastinal emphysema
[G. pneuma, air, + mediastinum]
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Examples: glitazone, GI cocktail, etc.