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plexiform neurofibroma


Definition: a type of neurofibroma, representing an anomaly rather than a true neoplasm, in which the proliferation of Schwann cells occurs from the inner aspect of the nerve sheath, thereby resulting in an irregularly thickened, distorted, tortuous structure; in some instances, the process extends along the course of the nerve and may eventually involve the spinal roots and the spinal cord; seen most frequently in neurofibromatosis.

Synonym(s): fibrillary neuroma, plexiform neuroma

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© Copyright 2018 Wolters Kluwer. All Rights Reserved. Review Date: Sep 19, 2016.