Definition: The creation of a fibrous adhesion between the visceral and parietal layers of the pleura, thus obliterating the pleural cavity; it is performed surgically by abrading the pleura or by inserting a sterile irritant into the pleural space, and applied as treatment in cases of malignant pleural effusion, recurrent spontaneous pneumothorax, and chylothorax.
[pleuro- + G. desis, a binding together]
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